Best Nootropics

Pass Exams
Sharp Focus
Stimulate Your Mind
Enhance Memory & Recall
Boost Creativity
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Join the millions of people already extending their limits and enhancing cognitive performance, choose drug from best nootropics list below.



Brand name: Olmifon
Chemical name: benzhydrylsulphinyl-acetohydroxamic acid
Classification: stimulant
Description: Adrafinil is a mild central nervous system stimulant used in the treatment of fatigue and sleepiness. It is said to increase mental acuity and is sometimes marketed as a “eugeroic” (“causing good arousal”).



Brand name: Draganon, Sarpul, Ampamet
Chemical name: 1-(4-Methoxybenzoyl)-2-pyrrolidinone
Classification: learning, memory, neuro-protectant
Description: Aniracetam is said to improve memory recall, increase intellectual clarity, improve immune function, and generate feelings of health and well-being, particularly in the elderly. Though hundreds of research papers have been published about aniracetam its mechanism of action and function are not well understood.



Brand names: Dehydroepiandrosterone, Fidelin, OVIGYN-D
Chemical name: dehydroepiandrosterone
Claaification: anti-aging, memory, cognitive function
Description: DHEA is a steroid hormone produced by the adrenal gland; Natural levels drop with age. DHEA supplements are said to increase energy, enhance memory and cognitive function, improve immunity, and reduce the effects of stress.



Brand names: DMAE, Deanol
Chemical name: di-methyl-amino-ethanol
Classification: anti-oxidant, memory, learning
Description: DMAE is a precursor of choline and an anti-oxidant that is found naturally in the brain. It is said to improve memory and learning as well as increasing ability to concentrate.



Brand names: Attentil, Vigilor, BP 662, Piperazine
Chemical name: 1-(1,3-benzodioxol-5-ylmethyl)-4-[(4-chlorophenoxy)acetyl]piperazine
Classification: stimulant, learning, memory
Description: Fipexide is a mild stimulant that is thought to indirectly affect dopamine levels in the brain. It is said to improve short term memory, attention, learning, and cognition. There is a risk of serious liver damage and high fever with use. Fipexide, more commonly called by the brand name Attentil, is a drug developed in Italy in 1983. It is a psychoactive drug which means that this chemical substance acts primarily upon the central nervous system and could affect one’s brain functions, which in this case usually results in a change of mood, cognitive behavior, perception and learning.



Brand name: Neurontin, Aclonium, Novo-Gabapentin, Gralise, Horizant, Gabarone
Chemical name: 1-(aminomethyl)cyclohexanacetic acid
Classification: anticonvulsant, tranquilizer
Description: Gabapentin is prescribed — usually in combination with other medications — for the treatment of seizure disorders, though its anticonvulsant mechanism is not known. It is sometimes prescribed for the management of neuralgia (nerve pain) and has been prescribed off-label for the treatment of mood disorders, anxiety, and tardive dyskinesia (a neurological syndrome caused by the long-term use of neuroleptic drugs).



Brand names: GH-3, Procaine, Novocaine
Chemical name: 4-aminobenzoic acid 2-(diethylamino)ethyl ester
Classification: anti-aging, memory, cognition
Description: Gerovital is a combination of procaine with an anti-oxidant and preservative. It has been marketed as a anti-aging drug, but double-blind studies have shown no efficacy and significant health risks. It was banned by the FDA in 1982.



Brand names: G, Sodium Oxybate, Xyrem, Alcover
Chemical name: gamma-hydroxybutyrate
Classification: depressant intoxicant
Description: GHB is a sedative used both as a prescription sleep-aid and as a recreational intoxicant. It is known for its ability to induce a short (several hour) coma-like sleep at high doses. A number of GHB-related deaths in combination with its addiction potential led to it being controlled by Federal law in 1999.



Ginkgo biloba
Brand names: Maidenhair Tree, Kew Tree
Chemical name: ginkgolides, bilobalide
Classification: increases blood flow
Description: The extract of the Ginkgo leaves contains flavonoid glycosides and terpenoids (ginkgolides, bilobalides) and has been used pharmaceutically for hundreds of years. It has many alleged nootropic properties, and is mainly used as memory and concentration enhancer, and anti-vertigo agent. Ginkgo extract seems to have three effects on the human body: it improves blood flow (including microcirculation in small capillaries) to most tissues and organs; it protects against oxidative cell damage from free radicals; and it blocks many of the effects of PAF (platelet aggregation, blood clotting) that have been related to the development of a number of cardiovascular, renal, respiratory and CNS (Central Nervous System) disorders.



Human Growth Hormone
Brand names: HGH, Somatotropin, CB-311
Chemical name: adenohypophyseal growth hormone
Classification: anti-aging
Description: Human Growth Hormone is a protein produced by the pituitary gland to promote cell growth. It has been marketed as an anti-aging supplement though there is little evidence to support this claim and incidence of side effects is high.



Brand names: Hydergine, Gerimal, Niloric, Alkergot, Circanol, Deapril-ST, Redergin, Trigot
Chemical name: Dihydroergotoxine mesylate
Classification: anti-oxidant, memory, blood flow, dementia
Description: Ergoloid mesylate is a dihydrogenated ergot (Claviceps purpurea) derivative alkaloid used as a vasodilator agent. Ergoloid Mesylate is the only vasodilator that has shown mild benefits in the treatment of vascular dementia. It was approved by the FDA in 1951.



Brand names: Centrophenoxine, Lucidril, Acephen
Chemical name: (4-chlorophenoxy)acetic acid 2-(dimethylamino)ethyl ester
Classification: memory, anti-aging
Description: Meclofenoxate is broken down by the liver into DMAE and PCPA (parachlorphenoxyacetic acid). It has been shown to cause mild memory improvement in people with dementia and has been marketed as an anti-aging supplement.



Brand names: MEL, Melatonin, MLT, Circadin, Mela-T, Melatol, Melatonex, Melatonine, Melovine, MT6, Night Rest
Chemical name: N-[2-(5-methoxy-1h-indol-3-yl)ethyl]acetamide
Classification: sleep regulator
Description: Melatonin is a biogenic amine that is found in animals, plants and microbes. Aaron B. Lerner of Yale University is credited for naming the hormone and for defining its chemical structure in 1958. In mammals, melatonin is produced by the pineal gland. The pineal gland is small endocrine gland, about the size of a rice grain and shaped like a pine cone (hence the name), that is located in the center of the brain (rostro-dorsal to the superior colliculus) but outside the blood-brain barrier. The secretion of melatonin increases in darkness and decreases during exposure to light, thereby regulating the circadian rhythms of several biological functions, including the sleep-wake cycle. In particular, melatonin regulates the sleep-wake cycle by chemically causing drowsiness and lowering the body temperature. Melatonin is also implicated in the regulation of mood, learning and memory, immune activity, dreaming, fertility and reproduction. Melatonin is also an effective antioxidant. Most of the actions of melatonin are mediated through the binding and activation of melatonin receptors. Individuals with autism spectrum disorders (ASD) may have lower than normal levels of melatonin. A 2008 study found that unaffected parents of individuals with ASD also have lower melatonin levels, and that the deficits were associated with low activity of the ASMT gene, which encodes the last enzyme of melatonin synthesis. Reduced melatonin production has also been proposed as a likely factor in the significantly higher cancer rates in night workers.



Brand names: Provigil, Modavigil, Armodafinil, Nuvigil, Modiodal, Sparlon, Alertec
Chemical name: benzhydrylsulphinylacetamide
Classification: stimulant, wakefulness promoter, narcolepsy treatment
Description: Modafinil is a stimulant drug marketed as a ‘wakefulness promoting agent’ and is one of the stimulants used in the treatment of narcolepsy. Narcolepsy is caused by dysfunction of a family of wakefulness-promoting and sleep-suppressing peptides, the orexins, whose neurons are activated by modafinil. The prexin neuron activation is associated with psychoactivation and euphoria. The exact mechanism of action is unclear, although in vitro studies have shown it to inhibit the reuptake of dopamine by binding to the dopamine reuptake pump, and lead to an increase in extracellular dopamine. Modafinil activates glutamatergic circuits while inhibiting GABA.



Brand names: Neuractiv, Neuromet, Hydroxypiracetam, CT-848
Chemical name: 4-hydroxy-2-oxo-1-pyrrolidineacetamide
Classification: memory, cognitive enhancement
Description: Oxiracetam is similar to piracetam and is said to improve memory especially in the elderly. It is not approved by the FDA but is widely used in Europe.



Brand names: Dilantin, Dilantin Infatabs, Dilantin-125, Phenytek, Dilantin Kapseals, Phenytoin Sodium, Prompt, Di-Phen
Chemical name: 5,5-diphenyl-2,4-imidazolidinedione
Classification: anti-convulsant, general cognitive function, anxiolytic
Description: Phenytoin is an anti-convulsant which is said to improve mental functioning and increase IQ, memory, and learning. There is a long list of adverse and potentially dangerous side-effects associated with its use. An anticonvulsant that is used in a wide variety of seizures. It is also an anti-arrhythmic and a muscle relaxant. The mechanism of therapeutic action is not clear, although several cellular actions have been described including effects on ion channels, active transport, and general membrane stabilization. The mechanism of its muscle relaxant effect appears to involve a reduction in the sensitivity of muscle spindles to stretch. Phenytoin has been proposed for several other therapeutic uses, but its use has been limited by its many adverse effects and interactions with other drugs.



Brand names: Nootropyl, Nootropil, Lucetam, Noostan, Breinox
Chemical name: 2-oxo-1-pyrrolidineacetamide
Classification: cognitive enhancement, memory, learning
Description: Piracetam is considered the first smart drug and is still one of the most popular. It is said to increase cognitive functions including memory and learning. Piracetam positively supports normal healthy cognitive & cardiovascular functioning by a multifaceted means of action. Approved & used since 1970’s worldwide (by various Health agencies in Europe, Asia, and South American) for improving health. Piracetam is recommended by many healthcare professionals and health organizations, such as the Life Extension Foundation and the American Academy of Anti-aging Medicine (A4M).



Brand name: CI-879
Chemical name: 2-(2-oxopyrrolidin-1-yl)-N-[2-(diisopropylamino)ethyl]acetamide
Classification: cognitive enhancement; memory
Description: Pramiracetam is similar in nature to piracetam though more potent and less-well researched. It is said to enhance memory and cognitive function.



Brand names: Deprenyl, Eldepryl, Emsam, Carbex, Gen-Selegiline, Jumex, Zelapar
Chemical name: (R)-N,a-dimethyl-N-2-propynylbenzeneethanamine
Classification: antidepressant, anti-aging, MAOI-B, MAOI-A (large doses)
Description: A selective, irreversible inhibitor of Type B monoamine oxidase. It is used in newly diagnosed patients with Parkinson’s disease. It may slow progression of the clinical disease and delay the requirement for levodopa therapy. It also may be given with levodopa upon onset of disability. (From AMA Drug Evaluations Annual, 1994, p385) The compound without isomeric designation is Deprenyl. After being sold for years as an anti-aging supplement and a treatment for Parkinson’s disease, the FDA approved use of a Selegiline transdermal patch (Emsam) for treatment of depression in 2006.



Brand names: L-tryptophan (precursor to 5-HTP), 5-HTP
Chemical name: L-tryptophan
Classification: sleep, mood
Description: L-Tryptophan is an essential amino acid, meaning the human body does not produce it naturally, but is required for the body’s healthy functioning. L-Tryptophan is present in a wide range of foods including beans, nuts, milk, and poultry. L-Tryptophan is a precursor to 5-HTP (which is a precursor to serotonin) and is sold as a sleep aid and mood enhancer. L-Tryptophan was banned by the FDA in the 1990s because of contamination in the production process, but was re-released onto the U.S. market in 2001 after the FDA published a revised estimate of the risks. During the 1990s, 5-HTP was sold for human consumption in the US and grew in popularity partially because L-Tryptophan was unavailable.



Brand names: ADH, Pressyn, Diapid, Pitressin, Biopressin, Desmopressin
Chemical name: antidiuretic hormone
Classification: memory
Description: Antidiuretic hormone, also known as vasopressin, is a nine amino acid peptide secreted from the posterior pituitary. Antidiuretic hormone binds to receptors in the distal or collecting tubules of the kidney and promotes reabsorbtion of water back into the circulation. When used as a ‘smart drug’, it is said to increase mental clarity and improve memory.



Brand names: Cavinton
Chemical name: ethyl apovincaminate
Classification: memory, vasodilator
Description: Vinpocetine is a derivative of vincamine from the periwinkle plant. It increases cerebral blood flow and is said to improve memory.


3 thoughts on “Best Nootropics

  1. HesterLee

    The term “nootropic” is composed from the Greek – “mind” and – “turn back, get in, change”. It was introduced in 1972 in order to describe the effect on the cognitive and sensitive sphere of the piracetam effects. Modapro, like other stimulants, increases the release of monoamines, such as dopamine and catecholamines of norepinephrine from the synaptic terminals. This function is considered a triggering factor of drug’s action in a human organism, though the precise mechanism of its action remains yet unknown.

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